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A sexually transmitted parasite that ’s extraordinarily widespread gets even more dangerous when infect with a virus , researchers say .
scientist enquire the sexually transmitted diseasetrichomoniasis , which is make by the parasiteTrichomonas vaginalis , a type of bug recognise as a protozoan . Rather than overrun human mobile phone , the sponge latches onto their surface and give on them .
Scientists have found the protozoanT. vaginalis(responsible for a sexually transmitted disease called trichomoniasis) becomes even more dangerous when infected with a parasite.
Trichomoniasis is more common than allbacterial sexually air diseasescombined , each year affecting most 250 million man and women worldwide . People infect with the parasite become specially vulnerable to other sexually transmitted diseases , include HIV , which make AIDS , and HPV , which is colligate with cervical and prostate Cancer . In accession , complication from trichomoniasis admit miscarriage , preterm manner of speaking , humble birth free weight and infertility .
" Trichomoniasis is associated with crushing consequences for women due to inflaming and related risks of reproductive disease , " say researcher Raina Fichorova , a reproductive immunobiologist at Harvard Medical School and Brigham and Women ’s Hospital in Boston .
Parasite - computer virus duo
Intriguingly , more than 80 percent of these sponger are themselves infected , with a virus plainly dubbedTrichomonasvirus . [ Quiz : try out Your STD Smarts ]
" Unlike flu viruses , for example , this computer virus ca n’t spread by jumping out of the cell into another one , " state researcher Max Nibert at Harvard Medical School . " It just spreads between cells when they [ the hosts ] divide or Ilex paraguariensis . "
The virus seems to have no prejudicial effect on the leech , and the far-flung nature of this virus led researchers to suspect it might actually profit the sponge in some means . To learn more , the research worker collectedTrichomonasfrom infected women and test how both computer virus - infected and virus - complimentary versions of the parasite affected human cell grow in lab dishes .
Currently , trichomoniasis is most often treated with the antibioticmetronidazole . However , when research worker kill virus - infectedTrichomonaswith this drug , they found the die or injured parasite discharge viruses that fire up the human cells .
The virus does not infect the human cell , but it nevertheless exacerbate the harmful effects of the parasite . These findings may explain why metronidazole does not prevent the harmful effects trichomoniasis can have onwomen ’s reproduction , and may really make affair worse — it forces the sponge to release harmful virus .
" Antibiotic treatment can actually make things worse by amplifying inflaming , " Fichorova enjoin .
make the body more vulnerable
The inflammation also might help excuse why the parasite makes masses more vulnerable to othersexually transmitted diseases(STDs ) . " The inflammation may destroy or weaken the barriers that keep other infections out , " Fichorova said .
Scientists are n’t sure whether the computer virus actually help the parasite in some direction . " The computer virus may convert the parasite ’s war paint — for example , help generate protein on the leech ’s airfoil that may subdue resistant response and make the parasite more acceptable to its host , " Fichorova pronounce .
succeeding research should search what part of the virus ' structure or life cycle may be most vulnerable to drug , Fichorova added . " To deal trichomoniasis safely , we have to not only attack this sponger , but also its virus at the same time . "
The scientists detailed their findings online Nov. 7 in the diary PLOS ONE .
