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coarse over - the counter and prescription medications known as anticholinergic drug can cause cognitive disability and can lead to dying , a unexampled survey says .
The chemical group includes over - the - counter ware containing diphenhydramine , prescription sopor aidsand incontinence treatments , many of which are frequently taken by older adult , the investigator said .
" Physicians should review with older patient role all the over - the - counter and prescription medicine drug they are taking to fix exposure , " said study researcher Dr. Malaz Boustani , an associate professor and aging researcher at Indiana University School of Medicine .
Older grownup and cognitive function
The two - year study looked at the affect of these medication on 13,000 work force and women age 65 , and is part of a big United Kingdom - ground study looking at health and cognitive function in old adults .
Anticholinergics strike the brain by blocking the neurotransmitter acetylcholine .
The drugs admit over - the - comeback medicament such as those sell under the brand names Benadryl , Dramamine , Excedrin post-mortem examination , Nytol , Sominex , Tylenol PM and Unisom , the researchers say . Other anticholinergic drugs , such as Paxil , Detrol , Demerol and Elavil are usable by prescription .
medicine with anticholinergic effect are used for many diseases , includinghypertension and congestive heart bankruptcy . The sketch found that those who were older , had low incomes and a greater number of wellness conditions were more likely to employ these medications . Women were more probable to report taking anticholinergic medications , due to the enceinte number of health conditions reported by women than by man .
More study needed
" We looked at drugs with either moderate [ or ] severe anticholinergic natural action . After align for age , sex activity , baseline mental status , education , income point , number of non - anticholinergic medication and health conditions , we found that taking anticholinergic medications was linked to cognitive impairment and for the first time to death , " said study researcher Dr. Chris Fox , a shrink at the University of East Anglia .
" We require follow - up to determine the degree to which anticholinergics are being prescribe for diseases with significant risk of death and the impact of that on our findings , " Fox said .
The bailiwick was published online today ( June 24 ) in the Journal of the American Geriatrics Society .
exceed it on : Anticholinergics may vitiate thought and increase the risk of dying .
