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Naked mole - rotter are among the unknown mammal on the planet . Not only do they live longer than any other gnawer ‒ up to 37 geezerhood ‒ they can also have babies well into old long time . Now , scientists think they ’ve make out how : The remarkable rodents ’ secret is that they never run out of ballock cells .
A new study , release today ( Feb. 21 ) in the journalNature Communications , investigated how naked mole - lowlife ( Heterocephalus glaber ) stay fertile , and the findings challenge the belief that mammals have a limited reserve of testis cells , established before or shortly after birth , and not replenished thereafter .
Not only are naked mole-rats (Heterocephalus glaber) the longest-living rodents, they also ‘never stop having babies,’ according to researchers.
" Naked mole - rat are the weirdest mammal , " head authorMiguel Brieño - Enríquez , an adjunct professor at Magee - Womens Research Institute and the University of Pittsburgh School of Medicine ’s Department of Obstetrics , Gynecology and Reproductive Sciences , said in astatement . " They ’re the longest - experience gnawer , they almost never getcancer , they do n’t feel pain like other mammals , they be in underground colonies , and only the queen can have child . But to me , the most awe-inspiring affair is that they never block off having babies . "
These hairless , burrowing creatures do n’t experience a drop in birth rate as they get older , unlike most other mammalian . But until now , scientist had no idea how .
relate : We expel carbon dioxide as barren . defenseless mole rats bath their brains in it to prevent seizure .
In the study , research worker liken the number of egg cell and death rate of these mobile phone in mice and au naturel seawall - dirty dog at unlike stages of development .
Most female mammal , including mice and world , are hold with a finite modesty of egg cells , which are by nature depleted over time .
But the scientist plant that this is not the causa with naked mole - bum . It turn out that naked mole - rat females are born without egg electric cell and give rise an exceptionally large number of them relative to their body size of it as pups . As well as endure longer than in mice , this ovarian reserve is replenished throughout the rodents ' life . The researchers spotted sign of orchis electric cell being bring forth in individuals up to 10 year old .
" This determination is sinful , " senior authorDr . Ned Place , a prof at the Cornell University College of Veterinary Medicine , pronounce in the statement . " It challenges the tenet that was established nearly 70 years ago , which stated distaff mammal are endow with a finite identification number of egg before or soon after giving birth , without any plus being made to the ovarian reserve thereafter . "
As well as adding to the naked groin - blackleg ’s long list of quirks , the researcher think these finding could direct to new therapies for humans .
defenseless mole - rats live in turgid settlement where only one dominant female can breed . When she is displaced or dies , subordinate female compete to become reproductively active . " Any female child can become a queen , " said Brieño - Enríquez .
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To find out more about the conversion from subordinate female to tabby , the scientists removed non - breeding female from the colony . In the absence seizure of a queen , predecessor ball cells in their ovaries go dividing — a foretoken of these females becoming reproductively fighting .
“ This is authoritative because if we can compute out how they ’re able-bodied to do this , we might be able to develop new drug targets or techniques to help human health , ” say Brieño - Enríquez . " Even though man are dwell longer , menopause still fall out at the same age . We hope to apply what we are learn from the naked groin - lowlife to protect ovary office later in life and prolong fertility . "
